Injectable depot compositions and uses thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 8252303
APP PUB NO 20040024069A1
SERIAL NO

10295814

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Abstract

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Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.

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Patent Owner(s)

Patent OwnerAddress
DURECT CORPORATION10260 BUBB ROAD CUPERTINO CA 95014

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Guohua Sunnyvale, US 140 4028
Houston, Paul R Hayward, US 33 1249
Kleiner, Lothar Walter Los Altos, US 22 582
Spaltro, John J Asbury, US 3 74

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