Composite hydrogel drug delivery systems
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United States of America Patent
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Aug 19, 2008
Grant Date -
Feb 19, 2004
app pub date -
Aug 12, 2003
filing date -
Aug 14, 1998
priority date (Note) -
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Abstract
Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species within relatively hydrophobic rate modifying agents to form a mixture. The mixture is formed into microparticles that are dispersed within bioabsorbable hydrogels, so as to release the water soluble therapeutic agents in a controlled fashion. Methods of using the compositions of the present invention in therapeutic systems are also provided.
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