Load-pulled haptomer-assisted detection
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United States of America Patent
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Issued Date -
Feb 26, 2004
app pub date -
Mar 19, 2003
filing date -
Mar 19, 2002
priority date (Note) -
Abandoned
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Abstract
High-sensitivity methods and systems for measuring small or trace concentrations of molecules of interest. A haptomeric material is positioned in contact with a fluid medium, and preferably within the peak E-field-volume of an electromagnetic probe. The haptomeric material will bind with high selectivity to the desired target substance (antigen), and the bound haptomer-antigen combination changes the observed dielectric properties, as seen from the electromagnetic probe. A load-pulled oscillator is the preferred detector configuration, but alternatively other electrical configurations can be used.
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