Sample generation for genotyping by mass spectrometry
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United States of America Patent
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Issued Date -
Feb 26, 2004
app pub date -
May 1, 2003
filing date -
Jun 30, 2000
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The invention is drawn to a universal method for preparing DNA samples for genotyping of single nucleotide polymorphisms (SNP), deletions and insertions by mass spectrometry. The invention relates to a method for genotyping that comprises three steps: a) reducing the complexity of the genome, b) generating allele specific products, c) analyzing the products by mass spectrometry, without purifying the products obtained in step b).
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