Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex

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United States of America Patent

APP PUB NO 20040038339A1
SERIAL NO

10239656

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a multifunctional polypeptide comprising a first domain comprising a binding site specifically recognizing an extracellular epitope of the NKG2D receptor complex and a second domain having receptor or ligand function. Furthermore, the present invention relates to polynucleotides encoding the multifunctional polypeptide, to vectors comprising said polypeptides and to cells comprising said polypeptides or said vectors. The invention also relates to compositions comprising either of the above recited molecules, alone or in combination, as well as to specific medical uses of the multifunctional polypeptide of the invention.

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Patent Owner(s)

Patent OwnerAddress
MICROMET AGMUNICH GERMANY MUNICH BAVARIA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Borschert, Katrin Munich, DE 2 153
Hofmeister, Robert Germering, DE 32 450
Kischel, Roman Munich, DE 43 1316
Kufer, Peter Moosburg, DE 106 2671
Lutterbuse, Ralf Munich, DE 6 536
Mayer, Monika Ottobeuren, DE 1 143
Rietmuller, Gert Munich, DE 1 143

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