Substituted phenylalkanoic acid derivatives and use thereof
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United States of America Patent
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Mar 15, 2005
Grant Date -
Mar 4, 2004
app pub date -
Feb 20, 2003
filing date -
Feb 21, 2002
priority date (Note) -
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Abstract
A compound represented by the formula (I) or a salt thereof: ##STR1## wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R.sup.1 (CH.sub.2).sub.k -- (wherein k represents 0 or an integer of 1 to 3; R.sup.1 represents a saturated cyclic alkyl group having 3 to 7 carbon atoms or a saturated condensed cyclic alkyl group having 6 to 8 carbon atoms, and the group R.sup.1 may be substituted with a lower alkyl group having 1 to 4 carbon atoms) and the like, and Ar represents a condensed bicyclic group such as naphthalen-1-yl group, which has suppressing action on prostaglandin and leukotriene production and is useful for prophylactic and/or therapeutic treatment of various inflammatory diseases and the like caused by these lipid mediators.
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