Tissue-engineered vascular structures
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United States of America Patent
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Issued Date -
Mar 4, 2004
app pub date -
Sep 19, 2003
filing date -
Oct 30, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention is directed to novel, less invasive and improved methods of tissue-engineering of constructs that require an endothelial surface such as blood vessels and heart valves. The constructs of the present invention possess long-term patency. The method of the present invention is particularly suited for making small diameter vessels to replace clogged or damaged coronary blood vessels, for making trileaflet heart valve conduits to replace damaged or malformed pulmonic and aortic valves, and for other vascular structures that require an endothelial surface.
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