System and method for encapsulating biological material by applying electrostatic charge to capsules
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United States of America Patent
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Issued Date -
Mar 11, 2004
app pub date -
Sep 11, 2003
filing date -
Jul 5, 2000
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A method and system for the effective and consistent encapsulation of viable (i.e., living or physiologically active) biological material (preferably, pancreatic islets also known as islets of Langerhans) with a polymeric material (preferably, a biocompatible semipermeable alginate) to form a gelled capsule, which can be transplanted into genetically dissimilar hosts. The method includes an electrostatic mixing process for producing encapsulated cell clusters with at least two polymeric coatings, and the system includes an improved spinning disk atomizer.
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