Methods for screening compound libraries
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United States of America Patent
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Issued Date -
Mar 18, 2004
app pub date -
Aug 14, 2003
filing date -
Mar 27, 1998
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Disclosed are methods for screening compound libraries using frontal chromatography in combination with mass spectrometry to identify and rank those members of the library that bind to a target receptor. Methods are also disclosed which permit a compound library to be rapidly screened to determine if any member of the library has an affinity for the target receptor as measured by a pre-selected indicator compound.
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