Electronic sensing of biomolecular processes
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United States of America Patent
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Issued Date -
Apr 8, 2004
app pub date -
May 8, 2003
filing date -
May 8, 2002
priority date (Note) -
Abandoned
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Abstract
The disclosure provided herein describes methods for the detection of conformational changes and/or interactions between biomolecules and molecules which bind to the biomolecules. The method is based on detection of alterations in resistance of a semiconductor nanostructured material coupled to a biomolecule where the resistance is modulated by the conformational state of biomolecules such that a change in the level of resistance so measured provides an indication of a change in the conformation of the biomolecule.
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