Agents affecting thrombosis and hemostasis
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United States of America Patent
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app pub date -
Nov 13, 2003
filing date -
Sep 4, 1990
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Abandoned
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Abstract
Analogs of blood factors which are transiently inactive are useful in treatment of diseases characterized by thrombosis. In addition, modified forms of activated blood factors that generate the active blood factor in serum but have extended half-lives are useful in treating hemophilic conditions. These modified forms of the blood factor may be acylated forms which are slowly deacylated in vivo.
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