Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
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United States of America Patent
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Mar 27, 2007
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N/A
app pub date -
Oct 6, 2003
filing date -
Sep 18, 1998
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Abstract
Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
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