Inhibition of restenosis using a DNA-coated stent
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United States of America Patent
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Issued Date -
Apr 15, 2004
app pub date -
Jun 9, 2003
filing date -
Dec 7, 2000
priority date (Note) -
Abandoned
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Abstract
Restenosis of arteries after angioplasty is inhibited by implanting in the treated artery a stent incorporating genes that encode gene products having anti-restenotic activity. The genes may be incorporated into a coating on the stent structure or in cells that are affixed to the stent. The genes or cells containing them may be adhered to the struts of the stent or incorporated in a collagen matrix that forms a coating covering the struts and interstices of the stent
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