Compounds, compositions as carriers for steroid/nonsteroid anti-inflammatory; antienoplastic and antiviral active molecules
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United States of America Patent
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Jan 2, 2007
Grant Date -
Apr 22, 2004
app pub date -
Jul 8, 2003
filing date -
Jul 8, 2002
priority date (Note) -
Expired
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Abstract
The present invention relates (a) to new compounds represented by Formula I: ##STR00001## wherein M represents a macrolide subunit (macrolide moiety) derived from macrolide possessing the property of accumulation in inflammatory cells, V represents an anti-inflammatory steroid or nonsteroid subunit, or an antineoplastic or antiviral subunit and L represents a linking group covalently linking M and V; (b) to their pharmacologically acceptable salts, prodrugs and solvates, (c) to processes and intermediates for their preparation, and (d) to their use in the treatment of inflammatory/neoplastic/viral diseases and conditions in humans and animals.
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