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Abstract

To track significant changes in a hemodynamic variable of a living body regardless of measurement noise induced by cyclical functions of the body, the hemodynamic variable is measured at substantially the same instant during several cycles and the measured values compared to identify any statistically significant changes. The measurements may be discrete or continuous. The heart may be stimulated by a cardiac device during some of the cycles and parameters of the device such as the A-V delay of a pacemaker may be adjusted in accordance with the measured change in the hemodynamic variable, which may be, among others, blood pressure or blood volume.

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First Claim