US Patent Application No: 2004/0082,642

Number of patents in Portfolio can not be more than 2000

Novel estrogen receptor ligands and method III

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Abstract

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The present invention relates to compounds of formula (I) and derivatives thereof, in which the variables are as defined in the claims, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynecomastia, autoimmune disease, vascular smooth muscle cell profileration, obesity, incontinence, and cancer of the lung, colon, breast, uterus, and prostate.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
KARO BIO ABHUDDINGE0
MERCK & CO., INC.RAHWAY, NJ3255

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cheng, Aiping Huddinge, SE 15 4
Gillner, Mikael Stockholm, SE 4 8
Hammond, Milton Lloyd Somerville, NJ 4 7
Heck, James V Scotch Plains, NJ 34 210
Koehler, Konrad Huddinge, SE 8 17
Liu, Ye Beijing, CN 224 353
Mosley, Ralph Troy Roselle, NJ 3 5
Rahimi-Ghadim, Mahmoud Stockholm, SE 3 4

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