Defensins: use as antiviral agents
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United States of America Patent
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Issued Date -
May 13, 2004
app pub date -
May 30, 2003
filing date -
May 31, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention relates to inhibition of viruses, e.g., HIV, using defensins. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions, antibodies, peptides, nucleic acids, antisense nucleic acids, and ribozymes, that increase naturally occurring defensin expression or activity, thereby inhibiting HIV in a cell; as well as to the use of expression profiles and compositions in diagnosis and prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.
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