Anti-inflammatory bioactive glass particulates
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United States of America Patent
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Issued Date -
May 20, 2004
app pub date -
Nov 7, 2003
filing date -
Apr 29, 1999
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Compositions and methods for systemically minimizing the inflammatory effects of TNF-.alpha. are disclosed. The compositions include particles of bioactive glass with a particle size less than about 20 .mu.m, alone or in combination with anti-inflammatory agents and other therapeutic agents. The compositions can include an appropriate carrier for oral, intramuscular, intraperitoneal or intravenous administration. When administered to a patient, the particles bring about elevated levels of IL-6 and do not cause elevated levels of TNF-.alpha..
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