Use of cyclic 2,4-diphosphoclycerates (cdgp) and/or derivatives thereof in cosmetic and dermatological formulations

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United States of America Patent

APP PUB NO 20040097543A1
SERIAL NO

10344969

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Abstract

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The invention relates to the inclusion of the low molecular weight substance (compatible solute), cyclic 2,4-diphosphoglycerate (cDGP), from extremophilic micro-organisms and/or derivatives of said compound, for example, an acid, a salt, or an ester, in cosmetic or dermatological formulations for protection of the skin from environmental influences and to increase the regeneration capacity. According to the invention, cyclic 2,4-diphosphoglycerate is implicated in active cell protection of the endogenous cell radical traps, antioxidants, the DNA, cell membranes and further cell compartments, by means of a protective effect of the above, against damaging environmental effects, for example, UV radiation, IR radiation, and environmental stress (thermal, chemical and physical). The compatible solute may serve as co-solvent and penetration improver for other active ingredients added to the cosmetic formulation, in order to not only stabilise the above in the cosmetic formulation, but also for active transport into deeper skin layers.

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Patent Owner(s)

Patent OwnerAddress
BITOP GESELLSCHAFT FUR BIOTECHNISCHE OPTIMIERUNG MBHTHE FEDERAL REPUBLIC OF GERMANY WITTEN WITTEN NORTH RHINE-WESTPHALIA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Schwarz, Thomas Leichlingen, DE 258 1343

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