Cells in which activity of the protein involved in transportation of GDP-fucose is reduced or lost
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United States of America Patent
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Jul 6, 2010
Grant Date -
Jun 10, 2004
app pub date -
Apr 9, 2003
filing date -
Apr 9, 2002
priority date (Note) -
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Abstract
A cell in which the activity of a protein relating to transport of an intracellular sugar nucleotide, GDP-fucose, to the Golgi body is more decreased or deleted than its parent cell; a process for producing an antibody composition using the cell; a transgenic non-human animal or plant or the progenies thereof, in which genome is modified so as to have a decreased or deleted activity of a protein relating to transport of an intracellular sugar nucleotide, GDP-fucose, to the Golgi body; a process for producing an antibody composition from the animal or plant; and a medicament comprising the antibody composition.
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