Delivery of nonsteroidal antiinflammatory drugs through an inhalation route
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United States of America Patent
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Jul 4, 2006
Issued Date -
N/A
app pub date -
Dec 12, 2003
filing date -
May 24, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to the delivery of nonsteroidal antiinflammatory drugs (NSAIDs) through an inhalation route. Specifically, it relates to aerosols containing NSAIDs that are used in inhalation therapy. In a method aspect of the present invention, an NSAID is delivered to a patient through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises an NSAID, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles with less than 5% NSAID degradation products. In a kit aspect of the present invention, a kit for delivering an NSAID through an inhalation route is provided which comprises: a) a thin coating of an NSAID composition and b) a device for dispensing said thin coating as a condensation aerosol.
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