Object comprising an uncharged, functionalized hydrogel surface
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United States of America Patent
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N/A
Issued Date -
Aug 12, 2004
app pub date -
Mar 24, 2004
filing date -
May 9, 2001
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The invention relates to an object, such as a sensor or a microcavity with an uncharged, functionalized hydrogel surface, comprising a hydrogel, which has hydroxy groups to which organic molecules are bound. The molecules used have one or more radicals .LAMBDA. and one or more radicals B. Radical .LAMBDA. reacts with the hydroxy groups of the hydrogel when binding the organic molecule. Radical B is selected such that, after the organic molecule binds to the hydrogel, it reacts with a biomolecule having amino groups or thio groups without the use of one or more activation reagents. The invention also relates to a method for producing the inventive object and to novel organic molecules for binding biomolecules to a hydrogel.
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