Apparatus and method for using bi-directional capillary electrophoresis
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United States of America Patent
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Issued Date -
Aug 26, 2004
app pub date -
Feb 23, 2004
filing date -
Feb 21, 2003
priority date (Note) -
Abandoned
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Abstract
The present invention provides an apparatus and method of utilizing bi-directional capillary electrophoresis ('CE') device. In one embodiment, cations are drawn into a first uncharged channel towards a negative electrode and anions are drawn into a second uncharged channel towards a positive electrode. The uncharged channels allows for minimal interaction between the sample and the walls of the channel which allows for minimal sample loss. The present invention also provides a method of separating anions from cations. The method comprises delivering the mixture to a bi-directional CE device. Following delivery, cations are drawn into a first uncharged channel towards a negative electrode and anions are drawn into a second uncharged channel towards a positive electrode. In one aspect of the present invention, the bi-directional CE device engages a microfluidic proteome analysis system.
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