DNA sequences for human tumour suppressor genes
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United States of America Patent
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Issued Date -
Sep 2, 2004
app pub date -
Aug 7, 2003
filing date -
Feb 12, 2001
priority date (Note) -
Abandoned
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Abstract
A method for the diagnosis of a predisposition thereto, in a patient, comprising the steps of: (1) establishing the level of expression of a gene selected from the group consisting of PR domain containing 7 protein (PRDM7), CDT1 DNA replication factor (CDT1), charged multivesicular body protein 1/chromoatin modifying protein 1 (CHMP1), BTG3 associated nucleoprotein (BANP), BNO224, BNO36, BNO34, BNO208, BNO230 and BNO44; and (2) comparing expression of the gene to a baseline established from expression in normal tissue controls; wherein substantial variance from the baseline indicates that the patient is susceptible to cancer.
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