Electro-optical devices and methods for hybridization and detection
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United States of America Patent
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Dec 13, 2005
Grant Date -
Sep 2, 2004
app pub date -
Mar 11, 2004
filing date -
May 4, 2001
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The invention provides an apparatus and method for detection of a target molecule. The apparatus includes a probe labeled with a transition metal-ligand complex that hybridizes with the target to form an initial complex, a metal ion for doping the initial complex and forming a final complex, and a potential means for providing a potential to the final complex to produce a detectable signal indicating the presence of the target after redox reaction. The method of the invention teaches the steps of hybridizing a probe with an attached label to the target to produce an initial complex, adding a metal ion to the initial complex to form a final complex and applying a potential to the final complex to produce a measurable signal.
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