Purification of taxanes and taxane mixtures using polyethyleneimine-bonded resins
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United States of America Patent
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Oct 18, 2005
Grant Date -
Sep 23, 2004
app pub date -
Sep 18, 2003
filing date -
Mar 17, 2003
priority date (Note) -
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Abstract
This invention is directed to a method for isolating and/or purifying one or more taxanes from materials comprising taxanes. In one embodiment, the method comprises the steps of: (a) treating a taxane containing material with an amino containing material attached to a solid matrix, such as a polyethyleneimine-bonded silica chromatographic resin; (b) eluting the desired taxane compound from the resin; and (c) recovering the eluted taxane compound.
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