Process for producing recombined protein
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Issued Date -
Oct 28, 2004
app pub date -
Jan 27, 2003
filing date -
Jul 31, 2000
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
It is intended to provide a process for efficiently producing a recombinant protein free from the N-terminal methionine. In culturing a host transformed by an expression vector for expressing a gene-modified protein, the dissolved oxygen concentration in the liquid culture medium is controlled to about 1 ppm or lower. Thus, the ratio of the expression of a recombinant protein free from the N-terminal methionine is elevated compared with the case wherein no such control is performed.
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