Method and system for intravesicular delivery of therapeutic agents
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United States of America Patent
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Issued Date -
Dec 23, 2004
app pub date -
Oct 22, 2003
filing date -
Oct 22, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A therapeutic agent delivery implant for implantation into a patient's body comprises a resilient or flexible, at least partially hydrophobic reticulated elastomeric support scaffold; and a hydrophilic coating arranged on said scaffold, wherein said coating contains one or more therapeutic agents for release within the patient. Optionally the coating can contain microspheres or enzymes. In a preferred embodiment, the scaffold comprises a hydrophobic polyurethane, the coating comprises a hydrophilic polyurethane, and the implant has a hemispherical, bullet, football, cylindrical, spherical, or irregular shape. The implant can be delivered through a rigid or flexible delivery instrument that deploys the implant at a desirable site, whereby the implant expands to a size and shape substantially similar to its size and shape before insertion.
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