Non-invasive prenatal genetic diagnosis using transcervical cells
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United States of America Patent
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app pub date -
Aug 20, 2004
filing date -
Apr 3, 2003
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Abstract
A non-invasive, risk-free method of prenatal diagnosis is provided. According to the method of the present invention transcervical specimens are subjected to trophoblast-specific immuno-staining followed by FISH, PRINS, Q-FISH and/or MCB analyses and/or other DNA-based genetic analysis in order to determine fetal gender and/or identify chromosomal and/or DNA abnormalities in a fetus.
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