Proteins capable of binding to environmental hormones and process for producing the same
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United States of America Patent
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Issued Date -
Jan 27, 2005
app pub date -
Aug 31, 2004
filing date -
Mar 1, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention provides a protein capable of binding to an environmental hormone, which protein is supplemented with useful properties for measuring, quantifying and concentrating environmental hormones, such as high sensitivity, low cross-reactivity, unlikelihood of being influenced by interfering substances, and unlikelihood of being influenced by solvents. Specifically, the present invention provides a modified protein prepared by obtaining various genes for various antibodies with environmental hormones, and modifying, by gene recombination technology, various properties of the original antibody, such as affinity, avidity, cross-reactivity, resistance for interfering substance on antigen-antibody reaction, resistance for interfering substance on enzymatic color developing reaction, resistance for solvent and the like.
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