Controlled release polymer nanoparticle containing bound nucleic acid ligand for targeting
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United States of America Patent
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Jun 23, 2009
Grant Date -
Feb 17, 2005
app pub date -
Jun 4, 2004
filing date -
Jun 6, 2003
priority date (Note) -
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Abstract
The present invention relates to a conjugate that includes a nucleic acid ligand bound to a controlled release polymer system, a pharmaceutical composition that contains the conjugate, and methods of treatment using the conjugate. The controlled release polymer system includes an agent such as a therapeutic, diagnostic, prognostic, or prophylactic agent. The nucleic acid ligand that is bound to the controlled release polymer system, binds selectively to a target, such as a cell surface antigen, and thereby delivers the controlled release polymer system to the target.
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