Method for the preparation of enterolactone from matairesinol

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United States of America Patent

APP PUB NO 20050038268A1
SERIAL NO

10499482

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Abstract

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This invention concerns a method for the preparation of enterolactone. The method is characterized by the steps of a) transforming the phenolic hydroxyl groups of matairesinol to groups R, which are removable by hydrogenolysis, to give Compound B in Scheme 1, b) substituting the groups R in Compound B in Scheme 1 with hydrogen, to give bis-3,3'-O-methylenterolactone (Compound C), and c) converting the methoxy groups in bis-3,3'-O-methylenterolactone to hydroxyl groups to give enterolactone. The invention concerns also a new group of compounds having the formula of Compound B in Scheme 1.

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Patent Owner(s)

Patent OwnerAddress
HORMOS MEDICAL CORPORATIONITAINEN PITKAKATU 4 FI-20520 TURKU

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Eklund, Patrik Turku, FI 9 0
Lindholm, Anna Bandhagen, SE 2 0
Sjoholm, Rainer Piispanristi, FI 6 0

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