Sutures and surgical staples for anastamoses, wound closures, and surgical closures
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United States of America Patent
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Sep 13, 2011
Grant Date -
Feb 17, 2005
app pub date -
Sep 7, 2004
filing date -
Jul 31, 2002
priority date (Note) -
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Abstract
The invention relates to sutures and surgical staples useful in anastomoses. Various aspects of the invention include wound closure devices that use amphiphilic copolymer or parylene coatings to control the release rate of an agent, such as a drug or a biological material, polymerizing a solution containing monomers and the agent to form a coating, using multiple cycles of swelling a polymer with a solvent-agent solution to increase loading, microparticles carrying the agent, biodegradable surgical articles with amphiphilic copolymer coatings, and sutures or surgical staples the deliver a drug selected from the group consisting of triazolopyrimidine, paclitaxol, sirolimus, derivatives thereof, and analogs thereof to a wound site.
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