Rapid fluorescent labeling of tissue for microdissection using fluorescent specific binding agents

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United States of America Patent

APP PUB NO 20050042692A1
SERIAL NO

10903324

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Abstract

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Methods are disclosed for rapid and specific fluorescent staining of biological tissue samples that substantially preserve biological molecules such as mRNA. Methods for microdissecting tissue to obtain pure populations of cells or tissue structures based upon identifying and excising cells or tissue structures that are labeled with fluorescent specific binding agents are also included. A laser capture microdissection apparatus useful for identifying and isolating cells and tissue structures following rapid immunofluorescent staining is also disclosed.

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Patent Owner(s)

  • THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Liotta, Lance A Bethesda, MD 103 1454
Murakami, Hiroshi Miyagi, JP 280 4209
Spring, Kenneth R Rockville, MD 2 26
Star, Robert A Bethesda, MD 7 69

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