Methods, compositions and instruments to predict antimicrobial or preservative activity
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United States of America Patent
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Issued Date -
Feb 24, 2005
app pub date -
Aug 22, 2003
filing date -
Aug 22, 2003
priority date (Note) -
Abandoned
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Abstract
Methods, compositions and instruments for predicting antimicrobial or preservative activity of an antimicrobial or preservative agent are disclosed. Under the present invention, a composition containing a probe molecule with a chromophore is placed in an instrument comprising a source of light radiation and a detector. The antimicrobial or preservative agent is reacted with the probe molecule to change the probe molecule's interaction with the light radiation. During this interaction, the probe molecule acts as a surrogate for a microbial cell membrane and the antimicrobial or preservative agent acts at least to some degree against the probe molecule as it would against the microbial cell.
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