Method for the treatment or diagnosis of human pathologies with disseminated or difficult to access cells or tissues

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United States of America Patent

SERIAL NO

10766929

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Abstract

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Method for the treatment or diagnosis of pathologies either expressed in injured or pathological multiple sites in tissues or in the body or expressed in injured or pathological sites of tissues or cells in sites of the body, which are difficult to access, with said sites or areas in immediate proximity to said sites being the source of the release of chemotactic factors for endogenous macrophages, either spontaneously or upon suitable stimulation, wherein said treatment is carried out by administration to the body of an appropriate amount of exogenous monocyte derived cells, said monocyte derived cells being, in the case of treatment, loaded with corrective agents with respect to the pathologies to be treated, and with said monocyte derived cells having the properties of mobilisation towards the source of the above-said released chemotactic factors and in target the cells present in the vicinity of the said released chemotactic factors, and in the case of diagnosis, loaded with a marker enabling the detection of injured or pathological sites.

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Patent Owner(s)

Patent OwnerAddress
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I N S E R M)PARIS CEDEX 13

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bartholeyns, Jacques Bures-Sur-Yvette, FR 23 54
Chokri, Mohamed Strasbourg, FR 16 50
Dreyfus, Patrick A Clamart, FR 2 8
Garcia, Luis Saint-Denis, FR 89 801
Parrish, Elaine Saint-Denis, FR 2 8
Peltekian, Elise Paris, FR 3 12

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