Gasketless microfluidic device interface

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20050048669A1
SERIAL NO

10649073

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Gasketless interfaces between microfluidic devices and related systems or instruments are provided. A microfluidic device includes a plastically deformable outer layer defining at least one port. An external mating surface having a protruding feature is aligned with the fluidic port defined in the microfluidic device. An actuator depresses at least a portion of the protruding feature into the outer layer adjacent to the fluidic port to cause the protruding feature to plastically deform the outer layer so as to form a reverse impression of the feature. Preferred materials are non-degrading in the presence of and non-absorptive of samples and solvents typically utilized in performing liquid chromatography. Systems for performing chromatography utilizing gasketless interconnects and at least one method for fabricating a multi-feature seal plate are provided.

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Patent Owner(s)

Patent OwnerAddress
NANOSTREAM INC580 SIERRA MADRE VILLA PASADENA CA 91107

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hobbs, Steven E West Hills, CA 20 2021
Karp, Christoph D Pasadena, CA 37 3080

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