Conversion of liver stem and progenitor cells to pancreatic functional cells
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United States of America Patent
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Sep 17, 2004
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Oct 18, 2001
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Abstract
The subject invention a method for converting liver stem/progenitor cells to a pancreatic functional cell by transfecting said liver cells with a pancreatic development gene and/or by culturing with pancreatic differentiation factors. The resulting cells produce and secrete insulin protein in response to glucose stimulation.
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