Electrophoretic in situ tissue staining
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United States of America Patent
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Issued Date -
Apr 7, 2005
app pub date -
May 18, 2004
filing date -
May 19, 2003
priority date (Note) -
Abandoned
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Abstract
The present invention introduces a radically different way of accelerating biomolecule conjugates into tissue, and hence towards their targets for purposes of tissue staining. The invention provides for an order of magnitude improvement over the prior art diffusion process used to stain tissue. The invention comprises a method of tissue staining by applying an electric field to a tissue sample in the presence of an electrolyte and biomolecular conjugates of interest suspended in the electrolyte. Typical staining times are reduced to seconds as opposed to 30-120 minutes common in the prior art. The invention is also directed to devices for performing the method.
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