Large conductance calcium-activated K channel opener
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United States of America Patent
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Issued Date -
Apr 7, 2005
app pub date -
Sep 22, 2003
filing date -
Mar 14, 2003
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
There is disclosed a large conductance calcium-activated K channel opener comprising a compound of the formula (I): 1 wherein R.sup.1 is aminosulfonyl, alkylsulfonyl, etc., R.sup.2 is hydrogen or halogen, R.sup.3 and R.sup.4 are hydrogen, halogen, alkyl or alkoxy, Ring A is benzene, pyridine, etc., and Ring Q is pyrazol, isoxazol, etc., and Ring Q and Ring A may be combined to each other to form a fused ring of the formula: 2 where X is S or O, R.sup.5 is halogen, alkyl, etc., and R.sup.3 and R.sup.4 are the same as mentioned above, or a pharmaceutically acceptable salt thereof as an active ingredient.
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