Methods and apparatuses for characterizing refolding and aggregation of biological molecules
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United States of America Patent
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Issued Date -
Apr 14, 2005
app pub date -
Aug 25, 2004
filing date -
Feb 20, 2002
priority date (Note) -
Abandoned
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Abstract
The invention provides methods and apparatuses for characterizing the folding and aggregation dynamics of biological molecules. The methods and apparatuses of the invention can be used, for example, to identify conditions that facilitate refolding of a denatured protein and to identify compounds that modulate aggregation of a protein, including a denatured protein.
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