Particle formation
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United States of America Patent
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N/A
Issued Date -
Apr 21, 2005
app pub date -
Jan 7, 2004
filing date -
Jan 8, 2003
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Method for preparing a target substance in particulate form, by introducing into a particle formation vessel, through separate first and second fluid inlets respectively, (a) a solution or suspension of the target substance in a fluid vehicle (the 'target solution/suspension') and (b) a compressed fluid anti-solvent for the substance, and allowing the anti-solvent to extract the vehicle from the target solution/suspension so as to form particles of the target substance, wherein the target solution/suspension enters the vessel downstream of the point of entry of the anti-solvent and at a point which lies on or close to the main axis of anti-solvent flow, and wherein the anti-solvent has a sub-sonic velocity as it enters the particle formation vessel.
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