US Patent Application No: 2005/0090,612

Number of patents in Portfolio can not be more than 2000

Polymerization process and materials for biomedical applications

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A molded component or article for biomedical use is prepared from a crosslinkable non-water-soluble polymer which when crosslinked and saturated with water forms a hydrogel. The polymer is formulated as a composition containing a non-aqueous diluent in addition to the polymer, the diluent being present in a volumetric proportion that is substantially equal to the volumetric proportion of water in the hydrogel that would be formed when the polymer is crosslinked and saturated with water. The composition is cast in a mold where the composition is exposed to conditions that cause crosslinking to occur by a reaction to which the non-aqueous diluent is inert. The crosslinking reaction produces a molded non-aqueous gel which is then converted to a hydrogel by substituting an aqueous liquid such as water or physiological saline for the non-aqueous diluent. The use of a molding composition whose curing consists essentially entirely of crosslinking results in a molding process that entails little or no shrinkage, and dimensional integrity is maintained up through the formation of the hydrogel by using the non-aqueous diluent in essentially the same volumetric proportion as water in the hydrogel.

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Patent Owner(s)

Patent OwnerAddressTotal Patents
ZMS, LLCEMERYVILLE, CA0
A CALIFORNIA LIMITED LIABILITY CORPORATIONEMERYVILLE, CA0

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fan, Shaobin Castro Valley, CA 2 15
Hino, Toshiaki Berkeley, CA 18 93
Soane, David S Piedmont, CA 172 3674

Cited Art Landscape

Patent Info (Count) # Cites Year
 
Other [Check patent profile for assignment information] (1)
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THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (1)
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Ceskoslovenska akademie ved (1)
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TORAY INDUSTRIES, INC. (2)
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CIBA VISION CORPORATION (1)
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CLEARLAB UK LTD (1)
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BAUSCH & LOMB INCORPORATED (1)
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HYDROGEL VISION CORPORATION (2)
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Johnson & Johnson Vision Products, Inc. (3)
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CLARITY POLYMERS, LLC (1)
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ULURU INC. (1)
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BIOCOMPATIBLES UK LIMITED (1)
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* Cited By Examiner

Patent Citation Ranking

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Patent Info (Count) # Cites Year
 
EMERGENCE VENTURE PARTNERS, LLC (2)
8,497,023 Polyurethane-grafted hydrogels 1 2009
8,853,294 Polyurethane-grafted hydrogels 0 2013
 
JOHNSON & JOHNSON VISION CARE, INC. (6)
8,317,505 Apparatus for formation of an ophthalmic lens precursor and lens 1 2008
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7,905,594 Free form ophthalmic lens 6 2009
8,157,373 Free form ophthalmic lens 1 2011
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CLARITY POLYMERS, LLC (1)
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THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (1)
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BIOMIMEDICA, INC. (1)
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THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS OFFICE OF GENERAL COUNSEL - PSG IV (024) (1)
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* Cited By Examiner