Plasma surface graft process for reducing thrombogenicity
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United States of America Patent
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Issued Date -
May 12, 2005
app pub date -
Feb 9, 2004
filing date -
Mar 2, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
In accordance with the present invention, there is provided a novel process for modifying the surface properties of a material that is suitable for contact with animal tissue so as to enhance its hemocompatibility and make it less thrombogenic when in use. This process comprises: Exposing the surface of the material to plasma treatment conditions in order to create reactive groups on said surface; activating a molecule with an activator to produce a reactive molecular species capable of forming convalent bonds with the reactive groups created on the surface of the material to form convalent bonds. The invention further encompasses the materials produced by this process as well as devices, such as vascular prosthesis, that are comprised of these process-modified materials.
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