Composition and method for inducing bone growth and healing
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United States of America Patent
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Feb 1, 2011
Grant Date -
May 19, 2005
app pub date -
Feb 20, 2003
filing date -
Feb 20, 2002
priority date (Note) -
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Abstract
A composition and method for inducing bone growth and healing is provided. The composition is useful for promoting new bone synthesis, and to enhance the mechanical stability and longevity of orthopaedic implants. The composition includes a bone endogenous material which is used as raw material for the body's natural osteogenic mechanism to synthesize new bone. The composition is applied in a flow phase and then undergoes a phase change to a congealed phase. The resulting material has a dual mode porosity system, having a first order porosity to accommodate and promote convective diffusion of nutrient species into and through the material, and a second order porosity to accommodate osteoblastic migration therein without the need for osteoclastic resorption.
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