Process for producing dammarane sapogenins and ginsenosides
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United States of America Patent
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Issued Date -
May 26, 2005
app pub date -
Jul 21, 2004
filing date -
Jul 24, 2001
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
This invention relates to a process for producing sapogenins and ginsenosides comprising the steps of mixing a ginsenoside extract with water, mixing the ginsenoside extract and water with an alkali-metal alcoholate solution or a hydroxide-ethanol solution to produce a mixture; or, alternatively, mixing a ginsenoside extract with ethanol, mixing the extract and ethanol with alkali-metal alcoholates solution to produce a mixture. The resultant mixture is placed in a reaction tank so that the resultant mixture can undergo chemical reactions under high temperature and high pressure effective to produce sapogenins therefrom. The temperature of the reaction tank can range between 150-300.degree. C. and the pressure can range between 2.5 to 8.4 MPa. After the reaction is completed, an intermediate product of a mix of ginsenosides and sapogenins from the ethanol mixture is collected and the desired sapogenins and ginsenosides are separated from the intermediate product by silica-gel-column chromatography.
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