Enhancer sequence of the 5-aminolevulinic acid synthase gene
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United States of America Patent
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Issued Date -
Jun 2, 2005
app pub date -
Oct 8, 2004
filing date -
Apr 9, 2002
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Abandoned
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Abstract
Nucleic acid sequences mediating chemical compound induced 5-aminolevulinate synthase gene (ALAS1) expression are disclosed. Said sequences comprise at least a DR-4 binding site. Furthermore, in vitro methods for testing chemical compounds for modulation of heme and/or P 450 cytochromes synthesis are described.
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