Automated immunohistochemical and in situ hybridization assay formulations
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United States of America Patent
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Jun 23, 2009
Grant Date -
Jun 2, 2005
app pub date -
Mar 7, 2002
filing date -
Sep 3, 1998
priority date (Note) -
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Abstract
Provided herein are reagents for use in an automated environment for cell conditioning of biological samples wherein the cells or tissues are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The reagents include, but are not limited to, components optimized to facilitate molecular access to cells and cell constituents within the biological sample. Also provided herein are reagents for use in an automated environment for removing or etching embedding media by exposing a biological sample to be stained in histochemical or cytochemical procedures without the dependence on organic solvents. The reagents include, but are not limited to, components optimized to facilitate removal or etching of the embedding media from the biological sample.
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