Designed protein pores as components for biosensors
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United States of America Patent
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Issued Date -
Jun 16, 2005
app pub date -
Sep 21, 2004
filing date -
Jul 25, 1997
priority date (Note) -
Abandoned
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Abstract
A mutant staphylococcal alpha hemolysin polypeptide containing a heterologous analyte-binding amino acid which assembles into an analyte-responsive heptameric pore assembly in the presence of a wild type staphylococcal alpha hemolysin polypeptide, digital biosensors, and methods of detecting, identifying, and quantifying analytes are described.
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