Pharmaceutical discovery and development
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
N/A
Issued Date -
Jul 7, 2005
app pub date -
Feb 18, 2005
filing date -
Mar 18, 2002
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
Serial electrochemical flow cells coupled in-line with electrospray ionization mass spectrometry (MS) provides rapid electrochemical (EC) study of biologically relevant oxidation-reduction (redox) reactions. Compounds, introduced by flow injection, are subjected to rapid electrolysis and products were monitored by MS. Serial coulometric EC-MS allows high-throughput study of relative compound reactivity, resultant formation of 'related substances' and determaination of metabolic and chemical 'soft spots.' Serial coulometric EC-MS thus represents a mechanistic probe that can be consistently and reproducibly applied to large compound libraries to generate 'modeling friendly' data for prediction and assessment of drug-like properties.
First Claim
Family
International Classification(s)
Cited Art Landscape
Patent Citation Ranking
Advertisement
Advertisement
Advertisement
Recipient Email Address
Recipient Email Address
Comment
Recipient Email Address
Add to Portfolio(s)
To add this patent to one, or more, of your portfolios, simply click the add button.
This Patent is in these Portfolios:
Add to additional portfolios:
Last Refreshed On:
Changes done successfully